Respiratory dead-space is often increased in lung disease. The carbon dioxide content of mixed exhaled gas (PECO2) is determined by the carbon dioxide content of the gas that came in contact with perfused alveoli (PACO2), the content of the gas that did not come in contact with perfused alveoli, and the proportion of the two.Background. Because this is a functional measurement. The physiological dead space is the sum of the anatomical and alveolar dead spaces, and represents all components of the tidal volume that do not take part in gas exchange.Dead space is that part of inspired air that is exhaled without the benefit of exposure to perfused alveoli.Bohr’s method measures the volume of the lung that does not eliminate CO2. However, this can be automatically converted to compatible units via the pull-down menu. Volume of Dead Space (V D): The calculator returns the volume in liters. ( P eCO 2) This is the partial pressure of carbon dioxide in exhaled air.( P aCO 2) This is the partial pressure of carbon dioxide in arterial blood.INSTRUCTIONS: Choose units and enter the following: The Physiologic Dead Space (Bohr Method) calculator computes the volume of dead space (V D) based on the tidal volume (V T) and the partial pressures of carbon dioxide in arterial blood, exhaled air and ambient air.
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